Genomics&Bioinformatics

2016年

第1讲:绪论

01-1-Introduction I-What is genome bioinformatics

01-2-Introduction II-How to do genome bioinformatics

基因组与基因组学(来自百度文库,作者:陈瑜)

第2讲:介绍主要数据库:GenBank, UCSC Genome browser, Ensemble, UniProtKB, PDB, EXPasy, KEGG, miRBase 等

02-1-Genome Bioinformatics Databases I

02-2-Genome Bioinformatics Databases II

提问和讨论环节:

  1. 请提前熟悉主要数据库的操作使用,带着问题来上课。
  2. 你用过哪些其他数据库?给大家演示一下。
  3. 你是否能提出新的数据库建设方案?
  4. 任何其他相关问题。

第3讲:序列比对

03-1-Pairwise sequence alignment

03-2 Multiple sequence alignment

提问和讨论环节:

  1. 双序列比对有哪些用途?
  2. 多序列比对软件有哪些?那个最好?

第4讲:BLAST搜索

04-3-Basic BLAST

04-4-Advanced BLAST

提问和讨论环节:

1.你在使用BLAST搜索数据库时,曾经碰到过什么问题?

2.高级BLAST有何用途?

第5讲:分子进化

05-1 Molecular Phylogeny

  1. 分子进化树和物种进化树含义有何不同?二者为何常常不一致?
  2. 蛋白质分子进化树和其编码基因的分子进化树为何常常不一致?如何解决?
 =============================================================================

Copyright notice

These PPT slides are compiled from some slides downloaded from the internet. Although I have made considerable modifications to make them up-to-date, the Copyright may still belongs to the original authors.

I was unable to clarify the original authors one by one for each of the slides, so I list their names and/or the websites here in the bottom.

These slides are used only for teaching and study, the users are only I myself and my students.

If you disagree my use of your material, please let me know, so that I will delete the part belongs to you.

 

1. Jonathan Pevsner, Bioinformatics and Functional Genomics,   (ISBN 0-471-21004-8). Copyright © 2003 by Wiley. http://www.bioinfbook.org

2. An Introduction to Bioinformatics Algorithms, Neil Jones and Pavel A. Pevzner   www.bioalgorithms.info

Leave a Reply